The synthesis and application of new nanocomposites based on inorganic, layered composites

In recent years, inorganic nanomaterials have been investigated in the fields of chemical, biological, and drug delivery. I investigate the synthesis and application of inorganic and organic nanocomposite materials that are life- and eco-friendly. I have also recently been studied biomolecules and drugs intercalated layered materials to be available applications for molecular containers, biomolecular carriers and drug delivery materials.
Layered double hydroxide (LDH) is well-known as hydrotalcite-like compound and inorganic nanomaterial. LDH has been considerable attention in recent years, owing to its potential technological properties such as materials for drug and gene delivery. The cellular uptake mechanism of LDH has also been investigated; however, the details of intracellular behavior and fate of LDH after internalization into cells have not clarified. In my research, to investigate cellular uptake behavior and intracellular traffic of LDH, a fluorescent LDH would be required to visualize and define in cell; therefore, I investigate the intercalation of fluorescent dye into LDH. I also study the synthesis of the anticancer drug/LDH in order to promote the cellular uptake of 5-FU.